For those not familiar with the game, it’s based on a futuristic Earth controlled by megacorporations and a pervasive computer network (the Matrix), yet filled with magic and mythical creatures. Characters can be samurai, shamans, deckers, or a variety of other archetypes.
The changes from 4th to 5th edition Shadowrun aren’t drastic. The cyberpunk aspects have been modernized a bit. Hacking the matrix has been simplified some, mostly to make it’s mechanics and timeline more consistent with other tasks. Gear quality now places a limit on dice pool hits. And magic has been tweaked some.